Omiganan kills acne causing bacteria by disrupting the bacterial cell membranes. It also is anti-inflammatory, specifically reducing bacteria induced inflammation.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C90H127N27O12 |
M.W/Mr. | 1779.14508 |
Sequence | H-Ile-Leu-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-Lys-NH2 |
Application | For treatment in bacterial infection and rosacea. |
Biological Activity | Omiganan Free Base is used for treatment of Mupirocin-resistant MRSA skin infections. |
Areas of Interest | Infection |
Target | Antimicrobial |
Source# | Synthetic |
BoilingPoint | N/A |
Melting Point | N/A |
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
2. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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