Palmitoyl Tetrapeptide-20 is a synthetic peptide consisting of a tetrapeptide sequence conjugated to palmitic acid for enhanced skin penetration. Widely utilized in cosmetic formulations, it is valued for its ability to support the appearance of skin firmness and smoothness. This ingredient is compatible with a range of topical applications, including facial serums and creams, and is suitable for use in global markets in accordance with cosmetic regulations.
CAT No: CPO-004
Mechanism of Action (MOA)
Palmitoyl Tetrapeptide-20 is a biomimetic signaling peptide conjugated with a palmitoyl lipid chain to enhance skin penetration. It interacts with cellular receptors in the epidermis, modulating key signaling pathways associated with skin homeostasis. Through its tetrapeptide sequence, it influences the expression of proteins involved in cellular communication and extracellular matrix support, contributing to optimized skin barrier function and balanced cellular activity without disrupting physiological processes.
Palmitoyl Tetrapeptide-20 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums and creams- Eye contour gels and lotions- Anti-aging emulsions- Sheet masks and leave-on treatments- Lightweight lotions for daily care- Formulations targeting delicate skin areas
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
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