Palmitoyl Tripeptide-38

Palmitoyl Tripeptide-38 is a synthetic lipopeptide composed of three amino acids linked to a palmitic acid chain, designed for use in advanced cosmetic formulations. Recognized for its biomimetic properties, this peptide supports the optimization of skin conditioning and smoothing applications. Its compatibility with a range of topical products makes it suitable for formulations targeting the appearance of fine lines and promoting overall skin suppleness in personal care products.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1754

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C33H65N5O7S
M.W/Mr.
675.96
Sequence
One Letter Code: Palm-KTTKS
Three Letter Code: Palmitoyl-Lys-Thr-Thr-Lys-Ser
Appearance
white powder

Mechanism of Action (MOA)

Palmitoyl Tripeptide-38 is a matrikine-mimetic peptide that interacts with the skin’s extracellular matrix by signaling to dermal fibroblasts. Through biomimetic activity, it modulates the expression of key matrix proteins such as collagen, fibronectin, and hyaluronic acid. This peptide supports cell–matrix communication, contributing to the maintenance of the skin’s structural integrity and extracellular matrix homeostasis via targeted cellular pathways.

Palmitoyl Tripeptide-38 is a versatile peptide suitable for various cosmetic formulations.

- Ideal for incorporation into facial serums and creams
- Compatible with anti-aging and moisturizing products
- Suitable for eye contour formulations
- Can be used in leave-on masks and treatments
- Appropriate for day and night skincare routines
- Stable in emulsions and gel-based systems

Source#
Synthetic
Long-term Storage Conditions
slightly soluble in water

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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