Pentafluoro-L-Phenylalanine is a fluorinated, non-proteinogenic amino acid derivative in which the phenyl side chain of phenylalanine is substituted with five fluorine atoms, retaining the amino acid backbone with a primary amino group and a carboxyl group. The molecule bears the stereochemical designation "L" at the alpha carbon and presents a highly electron-withdrawing, perfluorinated aromatic functionality that can alter polarity, hydrogen-bonding patterns, and aromatic interactions relative to unsubstituted phenylalanine. It is used in peptide and protein structure-function studies, chemical biology labeling, and analytical method development where fluorinated aromatic residues provide distinct spectroscopic and physicochemical signatures for incorporation into synthetic peptide analogues or for comparative binding and reactivity investigations.
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More