Phenylsulfonyl-Sar-OH is a protected amino acid derivative featuring the Sar (sarcosine) amino acid framework bearing a phenylsulfonyl substituent on the nitrogen and a free carboxylic acid (-COOH) at the C-terminus. The molecule contains an N-sulfonamide functionality (phenylsulfonyl-NH-) that modifies the amino group's reactivity while presenting the carboxyl group for coupling, and the sulfonyl group provides chemoselective control by reducing undesired amine-based side reactions relative to an unprotected amino acid. Phenylsulfonyl-Sar-OH is used as a building block or intermediate in peptide-related synthesis and in the preparation of N-protected sarcosine derivatives for structure-activity studies, chemical labeling, and stepwise assembly of more complex amino acid and peptide structures.
CAT No: CP27138
CAS No:46376-16-3
Synonyms/Alias:Phenylsulfonyl-N-Me-Gly-OH
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