Phthaloyl-L-glutamic acid is a protected L-glutamic acid derivative in which the α-amino group of the glutamate side chain is acylated with a phthaloyl (phthalimido) moiety, yielding a substituted dicarboxylic amino acid framework. The molecule retains the glutamate carboxyl functional groups while bearing the phthaloyl-protected amino functionality, and its stereochemistry is specified as L at the α-carbon by the product name. In peptide chemistry and related synthetic work, this protected amino acid is used as a building block to control chemoselectivity during stepwise assembly of glutamate-containing peptides or to prepare glutamate analogues for structure-activity, conjugation, or analytical studies where the free amino group must be masked.
CAT No: CP00738
CAS No:340-90-9
Synonyms/Alias:N-Phthaloyl-L-glutamicacid;340-90-9;Phthaloyl-L-glutamicacid;N-Phthalyl-L-glutamicacid;L-2-Phthalimidoglutaricacid;N-PhthalimideL-glutamincacid;(S)-2-(1,3-Dioxoisoindolin-2-yl)pentanedioicacid;N,N-Phthaloyl-L-glutamicacid;CHEBI:75277;Glutaricacid,2-phthalimido-,L-;N-Phthalyl-L-glutaminsaure[German];BRN0090136;(2S)-2-(1,3-dioxoisoindol-2-yl)pentanedioicacid;L-Glutamicacid,N-phthaloyl-;C13H11NO6;NSC-43131;AC1Q5VEL;Lopac-P-1801;N,N-Phthaloylglutamicacid;N-Phthalyl-L-glutaminsaure;AC1L4NN4;NCIStruc1_000393;NCIStruc2_000629;Lopac0_000956;MLS001056748
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