Phthaloyl-L-glutamic acid

Phthaloyl-L-glutamic acid is a protected L-glutamic acid derivative in which the α-amino group of the glutamate side chain is acylated with a phthaloyl (phthalimido) moiety, yielding a substituted dicarboxylic amino acid framework. The molecule retains the glutamate carboxyl functional groups while bearing the phthaloyl-protected amino functionality, and its stereochemistry is specified as L at the α-carbon by the product name. In peptide chemistry and related synthetic work, this protected amino acid is used as a building block to control chemoselectivity during stepwise assembly of glutamate-containing peptides or to prepare glutamate analogues for structure-activity, conjugation, or analytical studies where the free amino group must be masked.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00738

CAS No:340-90-9

Synonyms/Alias:N-Phthaloyl-L-glutamicacid;340-90-9;Phthaloyl-L-glutamicacid;N-Phthalyl-L-glutamicacid;L-2-Phthalimidoglutaricacid;N-PhthalimideL-glutamincacid;(S)-2-(1,3-Dioxoisoindolin-2-yl)pentanedioicacid;N,N-Phthaloyl-L-glutamicacid;CHEBI:75277;Glutaricacid,2-phthalimido-,L-;N-Phthalyl-L-glutaminsaure[German];BRN0090136;(2S)-2-(1,3-dioxoisoindol-2-yl)pentanedioicacid;L-Glutamicacid,N-phthaloyl-;C13H11NO6;NSC-43131;AC1Q5VEL;Lopac-P-1801;N,N-Phthaloylglutamicacid;N-Phthalyl-L-glutaminsaure;AC1L4NN4;NCIStruc1_000393;NCIStruc2_000629;Lopac0_000956;MLS001056748

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M.F/Formula
C13H11NO6
M.W/Mr.
277.2
Abbr
Pht-Glu-OH
InChI
1S/C13H11NO6/c15-10(16)6-5-9(13(19)20)14-11(17)7-3-1-2-4-8(7)12(14)18/h1-4,9H,5-6H2,(H,15,16)(H,19,20)/t9-/m0/s1
InChI Key
FEFFSKLJNYRHQN-VIFPVBQESA-N
Canonical SMILES
C1=CC=C2C(=C1)C(=O)N(C2=O)C(CCC(=O)O)C(=O)O

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