Phthaloyl-L-isoleucine is a protected L-isoleucine derivative in which the amino group is acylated with a phthaloyl (phthalimide-derived) protecting group, yielding an amino acid class member with an isoleucine-derived branched aliphatic side chain. The molecule retains the carboxylic acid functionality of the amino acid while featuring the phthaloyl-protected amino group, and its stereochemistry is specified as L at the α-carbon. In peptide chemistry and related synthetic workflows, this protected analogue is used as a building block to control chemoselectivity during stepwise assembly of amino acid sequences and to support downstream conversion of the carboxyl group into peptide-coupling intermediates.
CAT No: CP01220
CAS No:29588-88-3
Synonyms/Alias:29588-88-3;(2S,3S)-2-(1,3-dioxoisoindol-2-yl)-3-methylpentanoicacid;Phthaloyl-L-isoleucine;Pht-lle-OH;AC1LGOCW;PHT-ILE-OH;N,N-Phthaloyl-L-isoleucine;CHEMBL2429922;MolPort-020-004-534;ZINC261903;AKOS023033848;AM81867;AM002668;FT-0698183
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