pJAK2(1001–1013)

Name: pJAK2(1001–1013)
Brand: Creative Peptides
SKU: OPO-006
Availability: MadeToOrder

pJAK2(1001-1013) is a small peptide antagonist of SOCS-1 that had both an antiviral effect in keratinocytes against HSV-1 as well as a synergistic effect on IFNγ induction of an antiviral state.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: OPO-006

Synonyms/Alias: L-Proline, L-leucyl-L-prolyl-L-glutaminyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-O-phosphono-L-tyrosyl-L-tyrosyl-L-lysyl-L-valyl-L-lysyl-L-α-glutamyl-; ((S)-2-((S)-2-((S)-2-((S)-2-((S)-2-((S)-1-(L-leucyl)pyrrolidine-2-carboxamido)-5-amino-5-oxopentanamido)-3-carboxypropanamido)-6-aminohexanamido)-4-carboxybutanamido)-3-(4-(phosphonooxy)phenyl)propanoyl)-L-tyrosyl-L-lysyl-L-valyl-L-lysyl-L-glutamyl-L-proline;

Quick Inquiry Custom Peptide Synthesis

DOTA-cyclo(RGDfK) acetate

Inquiry
Buserelin Acetate

Buserelin Acetate is an agonist of gonadotropin-releasing hormone receptor(GnRHR). Buserelin is a synthetic luteinizing hormone–releasing hormone (LHRH) analog.

Inquiry
Terlipressin Acetate

Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.

Inquiry
Angiotensin II

Angiotensin II human (Angiotensin II) is a vasoconstrictor that mainly acts on the AT1 receptor. Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis.

Inquiry
Glucagon

Glucagon (Porcine glucagon) is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon decreases the activity of HNF-4. Glucagon increases HNF4α phosphorylation.

Inquiry
Alarelin acetate

Alarelin acetate is a synthetic LH-RH agonist, and stimulates the release of FSH and LH from the pituitary gland. It is known for its induction of ovulation and used to treat endmometriosis.

Inquiry
Elcatonin Acetate

Elcatonin acetate inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine.

Inquiry
Terlipressin

Terlipressin is a synthetic triglycyllysine derivative of vasopressin with vasoconstrictive, antihemorrhagic, and antidiuretic properties. Upon intravenous administration, terlipressin, an inactive prodrug, is biotransformed to its active moiety, lysine vasopressin (LVP), a nonselective vasopressin analogue with affinity for vasopressin receptors V1 (V1a), V2 and V3 (V1b). As a V1 agonist, terlipressin increases systemic vascular resistance, particularly in the splanchnic area, resulting in a decrease of portal pressure. V1 binding also promotes platelet aggregation and glycogenolysis, while V3 binding induces adrenocorticotropic hormone (ACTH) secretion. Compared to vasopressin, terlipressin has a minimal effect on V2 receptors, which are responsible for promotion of water reabsorption in the collecting ducts of the kidney via stimulation of cyclic AMP production.

Inquiry
Deslorelin

Deslorelin is a gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (testosterone and oestrogen). It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit luteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland.

Inquiry
Fertirelin Acetate

Fertirelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

Inquiry

M.F/Formula	C76H117N17O23
M.W/Mr.	1635.85
Sequence	One Letter Code:LPQDKE-{pTyr}-YKVKEP Three Letter Code:Leu-Pro-Gln-Asp-Lys-Glu-{pTyr}-Tyr-Lys-Val-Lys-Glu-Pro