Pmc-S-methylisothiourea

Pmc-S-methylisothiourea is a protected amino acid derivative featuring an isothiourea functionality attached through sulfur, with the side-chain sulfur converted to a methyl-substituted isothiourea (S-methylisothiourea) motif. The molecule bears the amino and carboxyl functional groups of an amino acid framework while the side-chain is masked as a Pmc-protected sulfur-containing group (Pmc), which controls chemoselectivity by suppressing undesired sulfur reactivity during peptide-coupling and other stepwise transformations. In synthesis, it is employed as a side-chain-functionalized building block or intermediate for preparing peptides and related conjugates that require an isothiourea-derived handle for subsequent chemical modification or downstream crosslinking-style derivatization under controlled conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26567

CAS No:185674-98-0

Synonyms/Alias:Pmc-S-methylisothiourea;185674-98-0

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M.F/Formula
C16H24N2O3S2
M.W/Mr.
356.51
Size
1 g;5 g;
InChI
1S/C16H24N2O3S2/c1-9-10(2)14(23(19,20)18-15(17)22-6)11(3)12-7-8-16(4,5)21-13(9)12/h7-8H2,1-6H3,(H2,17,18)
InChI Key
HQHUGFRYEKXPQL-UHFFFAOYSA-N
Canonical SMILES
CC1=C2C(=C(C(=C1C)S(=O)(=O)N=C(N)SC)C)CCC(O2)(C)C

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