(Pro3)-Dynorphin A (1-11) amide is a dynorphin fragment with a proline substitution at position 3, impacting backbone flexibility and receptor binding. The modification helps stabilize the peptide and enhances its interaction with kappa-opioid receptors. Researchers use this analog in studies examining the role of dynorphins in pain modulation and neuropeptide receptor specificity. Its amide terminus improves its bioactivity in pharmacological assays.
CAT No: D05017
1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
2. Implications of ligand-receptor binding kinetics on GLP-1R signalling
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