[Pyr-1]-Apelin-13 is a pyroglutamyl-modified apelin ligand that enhances resistance to aminopeptidase degradation. Its structure preserves the C-terminal core required for receptor binding. The cyclic N-terminal residue influences peptide conformation and hydrophobic surface exposure. Researchers employ it to examine apelin signaling and ligand-receptor interface geometry.
CAT No: A22011
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
2. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
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