[Pyr-3]-beta-Amyloid (3-42) begins at residue three with a pyroglutamate that significantly affects aggregation and fibril formation. The modification increases hydrophobicity and alters early nucleation kinetics. Its sequence provides a model for truncated amyloid species found in misfolding studies. Researchers use it to investigate aggregation-prone states and peptide structural transitions.
CAT No: A13259
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