Pyroglutamyl-glutamyl-proline amide integrates a pyroglutamate cap with acidic and cyclic residues that influence backbone curvature. The peptide serves as a stable motif for hydrogen-bond and ring-conformation studies. Researchers analyze its behavior in enzymatic recognition and solvent interactions. Applications include structural modeling, peptide processing studies, and motif-function evaluation.
CAT No: R2506
CAS No:85541-78-2
Synonyms/Alias:85541-78-2;(Glu2)-TRH;pyroglutamyl-glutamyl-proline amide;Pglu-glu-pro-amide;pGlu-Glu-Pro-NH2;PYR-GLU-PRO-NH2;[Glu2]-TRH;NMJ3YG49SE;(4S)-5-[(2S)-2-carbamoylpyrrolidin-1-yl]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid;Pglu-glu-pronh2;Glp-glu-pronh2;Pyroglutamyl-glutamyl-prolineamide;PyroGLU-GLU-PRO AMIDE;Fertilization promoting peptide;Pyroglutamyl-glutamyl-prolinamide;(Glu2)-TRH Pyr-Glu-Pro-NH2;MFCD00076815;pGlu-Glu-Pro Amide;GLP-GLU-PRO-NH2;UNII-NMJ3YG49SE;pyroglutamylglutamylprolineamide;SCHEMBL1373186;CHEMBL3895280;CHEBI:183942;DTXSID501006105;HY-P3960;DA-69328;FG108676;CS-0634436;L-Prolinamide, 5-oxo-L-prolyl-L-alpha-glutamyl-;L-PROLINAMIDE, 5-OXO-L-PROLYL-L-.ALPHA.-GLUTAMYL-;(S)-5-((S)-2-carbamoylpyrrolidin-1-yl)-5-oxo-4-((S)-5-oxopyrrolidine-2-carboxamido)pentanoic acid;4-{[Hydroxy(5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl)methylidene]amino}-5-{2-[hydroxy(imino)methyl]pyrrolidin-1-yl}-5-oxopentanoic acid;
2. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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