S-p-Methylbenzyl-L-cysteine

Name: S-p-Methylbenzyl-L-cysteine
Brand: Creative Peptides
Rating: 5 (1 reviews)

S-p-Methylbenzyl-L-cysteine is a sulfur-bearing, proteinogenic amino acid derivative of L-cysteine in which the thiol side chain is substituted with an S-p-methylbenzyl group, forming a thioether rather than a free thiol. The molecule contains an amino group and a carboxyl group characteristic of cysteine derivatives, while the benzyl substituent on sulfur provides a hydrophobic aromatic side-chain element and alters redox and nucleophilicity relative to unmodified cysteine. In peptide chemistry and chemical biology workflows, this protected/derivatized cysteine analogue is used as a building block or intermediate to introduce a cysteine-derived residue with controlled sulfur functionality for peptide synthesis, conjugation handle management, and structure-activity or labeling studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00640

CAS No:42294-52-0

Synonyms/Alias:S-p-Methylbenzyl-L-cysteine;42294-52-0;(R)-2-Amino-3-((4-methylbenzyl)thio)propanoicacid;S-(4-METHYLBENZYL)-L-CYSTEINE;AmbotzHAA6090;H-Cys(4-Mbzl)-OH;H-Cys(4-Mebzl)-OH;CHEMBL64242;SCHEMBL1158095;CTK7D1100;MolPort-002-492-165;QOAPFSZIUBUTNW-JTQLQIEISA-N;ZINC4668208;ANW-57510;AKOS010379543;AM81681;AJ-51866;AK-81237;KB-60614;ST2414446;TC-146255;FT-0639783;X5783;K-8797

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

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M.F/Formula

C11H15NO2S

M.W/Mr.

225.3

Abbr

H-Cys(4-Mbzl)-OH

InChI

1S/C11H15NO2S/c1-8-2-4-9(5-3-8)6-15-7-10(12)11(13)14/h2-5,10H,6-7,12H2,1H3,(H,13,14)/t10-/m0/s1

InChI Key

QOAPFSZIUBUTNW-JTQLQIEISA-N

Canonical SMILES

CC1=CC=C(C=C1)CSCC(C(=O)O)N

1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

2. The effect of B-type allatostatin neuropeptides on crosstalk between the insect immune response and cold tolerance

3. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

4. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes

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