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S3 Fragment, ADF/cofilin

This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: P75018

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M.W/Mr.
1698
Sequence
One Letter Code: MASGVMVSDDVVKVFN
Three Letter Code: H-Met-Ala-Ser-Gly-Val-Met-Val-Ser-Asp-Asp-Val-Val-Lys-Val-Phe-Asn-OH
References
Wen, Z. et al. J. Cell Biol. 178, 107 (2007).

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