SH-Oligopeptide-1 is a synthetic peptide corresponding to human epidermal growth factor (EGF), widely utilized in cosmetic formulations for its role in supporting skin conditioning. By promoting optimal skin appearance and texture, SH-Oligopeptide-1 is suitable for use in a range of personal care products targeting the improvement of skin smoothness and suppleness. This ingredient is compatible with global cosmetic regulations and can be incorporated into serums, creams, and other topical applications.
Mechanism of Action (MOA)
SH-Oligopeptide-1, a recombinant human epidermal growth factor (EGF) peptide, interacts with epidermal growth factor receptors (EGFR) on the surface of skin cells. This binding initiates intracellular signaling cascades, including the MAPK/ERK and PI3K/AKT pathways, which are associated with cellular processes such as proliferation and differentiation. Through these biochemical interactions, SH-Oligopeptide-1 supports the maintenance of optimal skin cell function and homeostasis.
SH-Oligopeptide-1 can be incorporated into a variety of cosmetic formulations to enhance product performance.
- Suitable for use in facial serums and creams- Compatible with eye contour formulations- Can be added to sheet masks and hydrogel masks- Appropriate for inclusion in scalp and hair care products- May be used in post-procedure skincare preparations- Blendable with hydrating gels and emulsions
1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
2. Emu oil in combination with other active ingredients for treating skin imperfections
5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
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