Solanezumab is a humanized monoclonal IgG1 antibody which is directed against the mid-domain of the Aβ peptide. By sequestering Aβ, shifting equilibria between different species of Aβ, and removing small soluble species of Aβ that are directly toxic to synaptic function, it may exert benefit.
Peptide Library Construction and Screening
Powerful screening tools in biological and chemical research
M.F/Formula | C6396H9922N1712O1996S42 |
M.W/Mr. | 144000.1g/mol |
Labeling Target | Amyloid precursor protein (APP) |
Application | Solanezumab, or sola, binds the amyloid-β peptides that aggregate and form plaques in the brain that are an early pathological feature of Alzheimer's disease. |
Areas of Interest | Neurological Disease |
2. Cationic cell-penetrating peptides are potent furin inhibitors
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at info@creative-peptides.com. We will endeavor to provide highly satisfying products and services.