Solanezumab

Solanezumab is a humanized monoclonal IgG1 antibody which is directed against the mid-domain of the Aβ peptide. By sequestering Aβ, shifting equilibria between different species of Aβ, and removing small soluble species of Aβ that are directly toxic to synaptic function, it may exert benefit.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-180

CAS No:955085-14-0

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C6396H9922N1712O1996S42
M.W/Mr.
144000.1g/mol
Labeling Target
Amyloid precursor protein (APP)
Application
Solanezumab, or sola, binds the amyloid-β peptides that aggregate and form plaques in the brain that are an early pathological feature of Alzheimer's disease.
Areas of Interest
Neurological Disease

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