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substance P, Pro(9)-

Substance P, Pro(9)- features a modified neuropeptide sequence that highlights the impact of proline substitution on molecular geometry. The alteration restricts backbone flexibility and reshapes conformational equilibria. Researchers analyze its binding profiles and solvent-dependent structure. Use cases include motif-function exploration, peptide design, and receptor-mapping studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
substance P, Pro(9)-(CAS 104486-69-3)

CAT No: R2625

CAS No:104486-69-3

Synonyms/Alias:Substance P, pro(9)-;(Pro(9))substance P;[Pro9]-Substance P;Substance P, proline(9)-;104486-69-3;Substance P, 9-L-proline-;CHEMBL2372071;9-Pro-substance P;Substance p,9-L-proline-;UFBNSKYNZDUWSN-RZGVDQIZSA-N;HY-P2475;BDBM50070367;NCGC00167227-01;DA-48947;CS-0134464;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C66H102N18O13S
M.W/Mr.
1387.7
Sequence
One Letter Code:RPKPQQFFPLM
Three Letter Code:H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2
InChI
InChI=1S/C66H102N18O13S/c1-39(2)36-47(58(90)75-43(55(71)87)29-35-98-3)80-62(94)52-24-15-34-84(52)65(97)49(38-41-18-8-5-9-19-41)81-59(91)48(37-40-16-6-4-7-17-40)79-57(89)44(25-27-53(69)85)76-56(88)45(26-28-54(70)86)77-60(92)51-23-14-33-83(51)64(96)46(21-10-11-30-67)78-61(93)50-22-13-32-82(50)63(95)42(68)20-12-31-74-66(72)73/h4-9,16-19,39,42-52H,10-15,20-38,67-68H2,1-3H3,(H2,69,85)(H2,70,86)(H2,71,87)(H,75,90)(H,76,88)(H,77,92)(H,78,93)(H,79,89)(H,80,94)(H,81,91)(H4,72,73,74)/t42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-/m0/s1
InChI Key
UFBNSKYNZDUWSN-RZGVDQIZSA-N

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