Suc-Leu-Tyr-AMC

Name: Suc-Leu-Tyr-AMC
Brand: Creative Peptides
SKU: R0810
Availability: MadeToOrder

Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease), and used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; emission max: 460 nm). Suc-Leu-Tyr-AMC can also be cleaved by the Ti protease from E. coli.

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CAT No: R0810

CAS No: 94367-20-1

Synonyms/Alias: Suc-Leu-Tyr-AMC;Suc-LY-AMC;94367-20-1;Suc-Leu-Tyr-MCA;N-Succinyl-Leu-Tyr-7-amido-4-methylcoumarin;Suc-leu-tyr-nhmec;CHEBI:63170;N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide;Succinyl-leucyl-tyrosyl-4-methyl-7-coumarylamide;N-(3-carboxypropanoyl)-L-leucyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tyrosinamide;MFCD00057900;N-Succinyl-Leu-Tyr 7-amido-4-methylcoumarin;CALPAIN SUBSTRATE I;RIYLNECMTVNMSO-GOTSBHOMSA-N;AKOS040755211;FS110527;TS-08846;HY-135172;CS-0109694;Q27132434;4-((S)-1-((S)-3-(4-hydroxyphenyl)-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-4-oxobutanoic acid;L-Tyrosinamide,N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C29H33N3O8
M.W/Mr.	551.6
Sequence	One Letter Code:LY Three Letter Code:Suc-Leu-Tyr-AMC
Application	A fluorgenic substrate
Appearance	White to off-white powder
Purity	>98%
Areas of Interest	Cell Biology

Source#	Synthetic
Long-term Storage Conditions	Soluble in DMSO
InChI	InChI=1S/C29H33N3O8/c1-16(2)12-22(31-25(34)10-11-26(35)36)29(39)32-23(14-18-4-7-20(33)8-5-18)28(38)30-19-6-9-21-17(3)13-27(37)40-24(21)15-19/h4-9,13,15-16,22-23,33H,10-12,14H2,1-3H3,(H,30,38)(H,31,34)(H,32,39)(H,35,36)/t22-,23-/m0/s1
InChI Key	RIYLNECMTVNMSO-GOTSBHOMSA-N
Isomeric SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](CC(C)C)NC(=O)CCC(=O)O
BoilingPoint	945.5ºC at 760mmHg
Melting Point	N/A

1. Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction

2. TMEM16F and dynamins control expansive plasma membrane reservoirs

3. Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet

4. Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L

5. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

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