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Synonyms/Alias | Sulanemadlin;Sulanemadlin [INN];6BGF28R54M;Sulanemadlin [USAN];ALRN-6924;UNII-6BGF28R54M;CHEMBL5394570;1451199-98-6;ALRN6924;N-Acetyl-L-leucyl-L-threonyl-L-phenylalanyl-cyclo(D-R8-L-glutamyl-ltyrosyl-ltryptophanyl-L-alanyl-L-glutaminyl-L-leucyl-L-S5)-L-alanyl-lalanyl-L-alanyl-L-alanyl-lalanyl-D-alanylamide;Sulanemadlin [USAN:INN];Alrn 6924;WHO 11411;Sulanemadlin (USAN/INN);ALRN 6924 [WHO-DD];GLXC-27604;HY-P4210;BDBM50624183;CS-0650265;D12399;C2.11,C2.4-[(4E)-undec-4-ene-1,11-diyl](N-acetyl-Lleucyl-L-threonyl-L-phenylalanyl-L-alanyl-L-alpha-glutamylL-tyrosyl-L-tryptophyl-L-alanyl-L-glutaminyl-L-leucyl-D-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-D-alaninamide);D-Alaninamide, 42,112-(7E)-7-undecene-1,11-diyl-N-acetyl-L-leucyl-Lthreonyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-tyrosyl-L-tryptophyl-L-alanyl-L-glutaminyl-L-leucyl-D-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-; |
M.F/Formula | C95H140N20O23 |
M.W/Mr. | 1930.2 |
InChI | InChI=1S/C95H140N20O23/c1-50(2)44-69(106-60(13)117)88(133)113-76(59(12)116)91(136)111-72(46-61-30-24-23-25-31-61)90(135)115-95(15)43-29-22-20-18-16-17-19-21-28-42-94(14,92(137)105-58(11)82(127)103-56(9)81(126)102-55(8)80(125)101-54(7)79(124)100-53(6)78(123)99-52(5)77(97)122)114-89(134)70(45-51(3)4)108-84(129)67(38-40-74(96)119)107-83(128)57(10)104-86(131)73(48-63-49-98-66-33-27-26-32-65(63)66)110-87(132)71(47-62-34-36-64(118)37-35-62)109-85(130)68(112-93(95)138)39-41-75(120)121/h17,19,23-27,30-37,49-59,67-73,76,98,116,118H,16,18,20-22,28-29,38-48H2,1-15H3,(H2,96,119)(H2,97,122)(H,99,123)(H,100,124)(H,101,125)(H,102,126)(H,103,127)(H,104,131)(H,105,137)(H,106,117)(H,107,128)(H,108,129)(H,109,130)(H,110,132)(H,111,136)(H,112,138)(H,113,133)(H,114,134)(H,115,135)(H,120,121)/b19-17+/t52-,53+,54+,55+,56+,57+,58+,59-,67+,68+,69+,70+,71+,72+,73+,76+,94+,95-/m1/s1 |
InChI Key | VDLGAZDAHPLOIR-RLPDZDIMSA-N |
2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. Implications of ligand-receptor binding kinetics on GLP-1R signalling
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