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TAK-448

TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
TAK-448(CAS 1234319-68-6)

CAT No: R1703

CAS No:1234319-68-6

Synonyms/Alias:TAK-448;1234319-68-6;UNII-YO029HR229;MVT-602;TAK 448;YO029HR229;L-Tryptophanamide, N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-;(D-Tyr46,D-pya-(4)47,azagly51,arg-(me)53)-metastin-(46-54);TAK448;CHEMBL3924151;RVT-602;SCHEMBL12626550;GTPL10222;DTXSID401337050;HY-P0076;BDBM50196420;DB11975;DA-58253;CS-0016567;Q27294617;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C58H80N16O14
M.W/Mr.
1225.4
Sequence
One Letter Code: Ac-Y-Hyp-NTFGLRW-NH2
three Letter Code: Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2
InChI
InChI=1S/C58H80N16O14/c1-30(2)22-42(51(82)66-40(16-11-21-63-57(61)62-5)50(81)67-41(49(60)80)25-35-28-64-39-15-10-9-14-38(35)39)70-58(88)73-72-53(84)43(23-33-12-7-6-8-13-33)69-55(86)48(31(3)75)71-52(83)44(27-47(59)79)68-54(85)46-26-37(78)29-74(46)56(87)45(65-32(4)76)24-34-17-19-36(77)20-18-34/h6-10,12-15,17-20,28,30-31,37,40-46,48,64,75,77-78H,11,16,21-27,29H2,1-5H3,(H2,59,79)(H2,60,80)(H,65,76)(H,66,82)(H,67,81)(H,68,85)(H,69,86)(H,71,83)(H,72,84)(H3,61,62,63)(H2,70,73,88)/t31-,37-,40+,41+,42+,43+,44+,45-,46+,48+/m1/s1
InChI Key
MWXWMWSUUYXMRA-GRKBUMBKSA-N

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