Tetrapeptide-16

Tetrapeptide-16 is a synthetic peptide composed of four amino acids designed for use in cosmetic formulations targeting skin conditioning applications. This ingredient is relevant for its role in supporting the appearance of smoother, more even-toned skin by promoting optimal skin barrier function. Tetrapeptide-16 is suitable for incorporation into a variety of leave-on and rinse-off products, aligning with global cosmetic regulatory requirements for peptide-based actives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1767

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Sequence
One Letter Code: YSYV
Three Letter Code: Tyr-Ser-Tyr-Val
Appearance
white powder

Mechanism of Action (MOA)

Tetrapeptide-16 is a synthetic biomimetic peptide designed to interact with cellular signaling pathways involved in the skin’s extracellular matrix. It modulates communication between keratinocytes and fibroblasts, supporting the expression of key matrix proteins such as collagen and laminin. By influencing these pathways, Tetrapeptide-16 contributes to the maintenance of the skin’s structural integrity. This peptide is suitable for formulations targeting the visible attributes of skin resilience and smoothness.

Tetrapeptide-16 can be incorporated into a variety of cosmetic formulations to enhance product offerings. Suggested application directions include:

- Facial serums for daily skincare routines
- Moisturizing creams and lotions
- Eye contour gels and creams
- Sheet masks and leave-on treatments
- Lightweight emulsions for sensitive skin
- Night care products for regular use

Source#
Synthetic
Long-term Storage Conditions
soluble in water

Useful Tools

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Abbreviation List

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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