(Thr4,Gly7)-Oxytocin

(Thr4,Gly7)-Oxytocin is a modified oxytocin analog featuring threonine and glycine substitutions that influence receptor interaction and peptide stability. These changes alter the peptide's hydrophobicity and flexibility, providing insights into receptor-specific binding. The modified oxytocin retains its ability to stimulate uterine contractions, making it useful for exploring receptor subtype interactions. Researchers apply it in studies of peptide hormone signaling.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: O06001

Synonyms/Alias:(Thr4,Gly7)-Oxytocin;60786-59-6;Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2;MFCD00076735;Thr4-Gly7-Oxytocin;[Thr...4...,Gly...7...]OT;CHEMBL3249214;HY-P3467;DA-59716;CS-0609562;Glycinamide,l-cysteinyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinylglycyl-L-leucyl-,cyclic(1(R)6)-disulfide;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C39H61N11O12S2
M.W/Mr.
940.1
Sequence
One Letter Code:CYITNCGLG
Three Letter Code:H-Cys(1)-Tyr-Ile-Thr-Asn-Cys(1)-Gly-Leu-Gly-NH2
Length
9
InChI
InChI=1S/C39H61N11O12S2/c1-6-19(4)31-38(61)50-32(20(5)51)39(62)47-26(13-28(41)53)36(59)48-27(35(58)44-15-30(55)45-24(11-18(2)3)34(57)43-14-29(42)54)17-64-63-16-23(40)33(56)46-25(37(60)49-31)12-21-7-9-22(52)10-8-21/h7-10,18-20,23-27,31-32,51-52H,6,11-17,40H2,1-5H3,(H2,41,53)(H2,42,54)(H,43,57)(H,44,58)(H,45,55)(H,46,56)(H,47,62)(H,48,59)(H,49,60)(H,50,61)/t19-,20+,23-,24-,25-,26-,27-,31-,32-/m0/s1
InChI Key
XQAKKLKDUOWUIU-IKNHWLCZSA-N

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