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Tos-L-Arg-NH2*HCl

Tos-L-Arg-NH2*HCl is a protected L-arginine derivative in which the amino acid side chain retains the guanidinium functionality while the alpha-amino group is present as an amide-forming amino acid amine (L-Arg-NH2) and the tosyl (Ts) group provides N-protection. The molecule is supplied as a hydrochloride salt, pairing the basic sites to form a stable ionic form and supporting handling in peptide and amine chemistry, with the tosyl substituent controlling chemoselectivity by reducing undesired nucleophilicity at the protected nitrogen. In synthesis and chemical biology workflows, this compound is used as a building block or intermediate for preparing arginine-containing peptides and peptide-like amides, as well as for generating further arginine derivatives where controlled deprotection and subsequent coupling steps depend on the presence of the tosyl-protected amino functionality.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25350

CAS No:14279-64-2

Synonyms/Alias:Tos-Arg-NH2HCl;14279-64-2;Tos-L-Arg-NH2*HCl;C13H22ClN5O3S;SCHEMBL7319933;CTK8G3516;MolPort-003-916-043;6987AA;AKOS016003225;AK-81305;KB-301259;ST24031921;K-4575;N-Alpha-p-tosyl-L-arginineamidehydrochloridesalt;N~2~-[(4-Methylphenyl)sulfonyl]argininamidehydrochloride

Chemical Name:N-alpha-p-Toluolsulfonyl-L-arginine amide hydrochloride

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M.F/Formula
C13H22ClN5O3S
M.W/Mr.
363,89 g/mole
Size
5 g;25 g;
InChI
1S/C13H21N5O3S.ClH/c1-9-4-6-10(7-5-9)22(20,21)18-11(12(14)19)3-2-8-17-13(15)16;/h4-7,11,18H,2-3,8H2,1H3,(H2,14,19)(H4,15,16,17);1H/t11-;/m0./s1
InChI Key
ULGNEWYDCYUHJH-MERQFXBCSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NC(CCCN=C(N)N)C(=O)N.Cl

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