TIF2 (636-649), Transcriptional Intermediary Factor 2 (636-649), Box1, contains an LxxLL-like nuclear receptor interaction motif. Sequence architecture favors helical folding necessary for docking onto receptor AF-2 surfaces. Conformational flexibility is tuned for coactivator recruitment. Researchers use it to dissect cofactor-binding specificity and transcriptional regulation.
CAT No: S06069
Synonyms/Alias:TIF2 (636-649), Transcriptional Intermediary Factor 2 (636-649), Box1;
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