Trt-Gln(Trt)-OH · DEA is a protected glutamine derivative in which the side-chain amide is retained while both the α-amino functionality and the side-chain are masked by trityl (Trt) protecting groups, and the carboxyl group is present as a free acid (-OH). The molecule contains protected amino and amide-associated nitrogen atoms bearing trityl groups, and it is supplied as a complex/salt with diethylamine (DEA), which is consistent with an amine counterion environment that can influence handling and solubility. In peptide chemistry, this kind of trityl-protected amino acid building block is used as a precursor for stepwise assembly of glutamine-containing peptide sequences and for preparing protected intermediates where chemoselective deprotection and coupling control are required.
1. Myotropic activity of allatostatins in tenebrionid beetles
4. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
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