Z-β-Alanine N-hydroxysuccinimide ester

Name: Z-β-Alanine N-hydroxysuccinimide ester
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-β-Alanine N-hydroxysuccinimide ester is an amino acid derivative in which β-alanine is functionalized at the carboxyl terminus as an N-hydroxysuccinimide (NHS) ester, with a Z substituent on the amino acid framework. The molecule contains an NHS-activated ester that can undergo acyl transfer to nucleophiles such as primary amines, while the remaining amino functionality is configured according to the Z-protected form indicated by the name and the carboxyl group is masked as a leaving-group-containing ester rather than a free acid. In synthetic and bioconjugation workflows, this activated β-alanine derivative is used as a precursor for preparing amide-linked conjugates and for introducing a β-alanine spacer bearing an NHS-derived acyl functionality into larger peptide, protein, or polymer constructs.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP02310

CAS No:53733-97-4

Synonyms/Alias:Z-BETA-ALA-OSU;53733-97-4;2,5-DIOXOPYRROLIDIN-1-YL3-{[(BENZYLOXY)CARBONYL]AMINO}PROPANOATE;Z-?-Ala-OSu;SCHEMBL6420313;ZINC2561177;7862AH;AKOS025289387;AK170111;AM025244;HE009937;K-9716;Carbamicacid,[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-,phenylmethylester(9CI)

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cGMP Peptide

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M.F/Formula

C15H16N2O6

M.W/Mr.

320.3

Abbr

Z-β-Ala-OSu

InChI

1S/C15H16N2O6/c18-12-6-7-13(19)17(12)23-14(20)8-9-16-15(21)22-10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,16,21)

InChI Key

XBQSLJICWKEVSC-UHFFFAOYSA-N

Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)CCNC(=O)OCC2=CC=CC=C2

1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

2. The spatiotemporal control of signalling and trafficking of the GLP-1R

3. Quantitative Analysis of Ligands Effects on Bioefficacy of Nanoemulsion encapsulating Depigmenting Active

4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

5. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

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