Z-Arg(Boc)2-OH · CHA is a protected arginine derivative featuring the guanidinium-bearing arginine side chain and an N-benzyloxycarbonyl (Z/Cbz) protection on the α-amino group, with two tert-butoxycarbonyl (Boc) protecting groups on the guanidino functionality. The molecule is present as a salt with cyclohexylamine (CHA), and its carboxyl group is in the free acid form (-CO2H), while the Boc and Z groups mask the strongly basic nitrogens to control chemoselectivity during peptide coupling. This protected amino acid is used as a building block in peptide synthesis and related protection/deprotection workflows, where the protected guanidinium and α-amino functionalities support stepwise assembly of arginine-containing peptide structures and facilitate downstream analytical handling.
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