Z-Arg(Mtr)-OtBu is a protected arginine derivative featuring an Nα-benzyloxycarbonyl (Z) group on the amino terminus and a side-chain guanidinium protected as the Mtr (4-methoxy-2,3,6-trimethylbenzenesulfonyl-like) aryl sulfonamide-type protecting group, along with a tert-butyl ester (OtBu) at the carboxyl terminus. The molecule therefore contains the arginine backbone bearing a substituted guanidine functionality masked to reduce undesired reactivity, while the Z carbamate and OtBu ester provide chemoselectivity by suppressing amine and carboxyl participation during stepwise assembly. Z-Arg(Mtr)-OtBu is used as a peptide-building block in protected-amino-acid strategies, where its controlled functional group protection supports coupling and downstream deprotection to generate arginine-containing peptide intermediates for synthesis and structure-activity or labeling studies.
CAT No: CP26214
CAS No:115608-60-1
Synonyms/Alias:ZINC71788244;AKOS015908587;I14-34240;115608-60-1;L-Ornithine,N5-[imino[[(4-methoxy-2,3,6-trimethylphenyl)sulfonyl]amino]methyl]-N2-[(phenylmethoxy)carbonyl]-,1,1-dimethylethylester
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