Z-Arg(Pmc)-OH · CHA is a protected arginine derivative in which the alpha-amino group is masked as a benzyloxycarbonyl (Z) carbamate and the guanidino side chain is protected as a Pmc (2,2,5,7,8-pentamethylchroman-6-sulfonyl) group, yielding an arginine amino acid framework suitable for peptide chemistry. The molecule contains a free carboxylic acid (-COOH) and a protected guanidino functionality, with stereochemistry not specified in the provided name, and the "· CHA" indicates association with an additional component (commonly a counterion or solvate/form) that can affect handling and physical properties. In synthesis, the orthogonal protection pattern supports stepwise assembly of arginine-containing peptides by allowing chemoselective deprotection of the side-chain and/or amino protecting groups to control side-reaction pathways during coupling and subsequent fragment ligation.
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