Z-D-Arg(Pbf)-OH*CHA contains the amino acid arginine bearing a Pbf (2,2,4,6,7-pentamethylbenzofunctional) side-chain protecting group on the guanidinium functionality, with the alpha-amino and alpha-carboxyl groups present in a protected amino acid form and a Z (benzyloxycarbonyl) protecting group on the alpha-amino group. The "D" stereochemical designation indicates the D-configuration at the alpha-carbon, while the *CHA notation denotes an associated counterion/solvate form with choline, which can influence handling and crystallinity without changing the core arginine-derived scaffold. In peptide chemistry, this protected arginine building block is used in stepwise peptide synthesis workflows to control chemoselectivity by masking the reactive guanidinium and amino functionalities during coupling and subsequent deprotection steps.
CAT No: CP25552
CAS No:200191-00-0
Synonyms/Alias:Z-D-ARG(PBF)-OHCHA;200191-00-0;Z-D-Arg(Pbf)-OHHA;Z-D-Arg(Pbf)-OH.CHA;C33H49N5O7S;MolPort-020-003-865;CZ-099;ST24046385;X5197;K-5848;Z-D-Arg(Pbf)-OHinvertedexclamationmarkcurrencyCHA
Chemical Name:N-alpha-Benzyloxycarbonyl-N-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-D-arginine cyclohexylamine
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