Z-D-Dbu(Fmoc)-OH is a protected amino acid derivative featuring a D-stereochemical center and an amino acid backbone bearing a benzyl-type Z (carbobenzyloxy) protecting group on the α-amino functionality, along with an Fmoc (9-fluorenylmethoxycarbonyl) protecting group also associated with the amino functionality as indicated by the name. The side chain is an alkyl substituent (Dbu) and the molecule contains a free carboxylic acid group (-COOH) that can participate in peptide coupling chemistry while the protected amino functionality is masked to control chemoselectivity. In peptide synthesis workflows, this orthogonally protected amino acid analogue is employed as a stepwise building block for constructing peptide chains and for preparing peptide-related intermediates where selective deprotection and subsequent coupling at the carboxyl group are required.
CAT No: CP25217
CAS No:1217471-94-7
Synonyms/Alias:(S)-4-(Fmoc-amino)-3-(Z-amino)butyric acid;Z-Dbu(Fmoc) (S)
Chemical Name:(S)-N-beta-Benzyloxycarbonyl-N-gamma-(9-fluorenylmethyloxycarbonyl)-3,4-diaminobutyric acid
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