Z-D-Gln(Mtt)-OH

Z-D-Gln(Mtt)-OH is a protected amino acid derivative of glutamine in which the α-amino group is masked as a benzyloxycarbonyl (Z) carbamate and the side-chain amide is substituted with an Mtt (4-methyltrityl) protecting group. The molecule bears a free α-carboxylic acid functionality and a stereogenic center consistent with the D configuration as indicated by the product name, while the protected side-chain amide is rendered less nucleophilic to control chemoselectivity during peptide assembly. Z-D-Gln(Mtt)-OH is used as a building block in stepwise peptide synthesis and related peptide chemistry workflows where orthogonal protection of the side-chain amide supports selective deprotection and incorporation into peptide intermediates.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26667

CAS No:200716-85-4

Synonyms/Alias:200716-85-4;Z-D-Gln(Mtt)-OH;ZINC71788238;AKOS015909245;AM003559;I14-33068;(2R)-2-{[(BENZYLOXY)CARBONYL]AMINO}-4-{[(4-METHYLPHENYL)DIPHENYLMETHYL]CARBAMOYL}BUTANOICACID

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cGMP Peptide
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  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C33H32N2O5
M.W/Mr.
536.64
Size
1 g;5 g;
InChI
1S/C33H32N2O5/c1-24-17-19-28(20-18-24)33(26-13-7-3-8-14-26,27-15-9-4-10-16-27)35-30(36)22-21-29(31(37)38)34-32(39)40-23-25-11-5-2-6-12-25/h2-20,29H,21-23H2,1H3,(H,34,39)(H,35,36)(H,37,38)/t29-/m1/s1
InChI Key
FPSOCLFFNPGXTD-GDLZYMKVSA-N
Canonical SMILES
CC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CCC(C(=O)O)NC(=O)OCC4=CC=CC=C4

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