Z-D-Gln(Mtt)-OH is a protected amino acid derivative of glutamine in which the α-amino group is masked as a benzyloxycarbonyl (Z) carbamate and the side-chain amide is substituted with an Mtt (4-methyltrityl) protecting group. The molecule bears a free α-carboxylic acid functionality and a stereogenic center consistent with the D configuration as indicated by the product name, while the protected side-chain amide is rendered less nucleophilic to control chemoselectivity during peptide assembly. Z-D-Gln(Mtt)-OH is used as a building block in stepwise peptide synthesis and related peptide chemistry workflows where orthogonal protection of the side-chain amide supports selective deprotection and incorporation into peptide intermediates.
CAT No: CP26667
CAS No:200716-85-4
Synonyms/Alias:200716-85-4;Z-D-Gln(Mtt)-OH;ZINC71788238;AKOS015909245;AM003559;I14-33068;(2R)-2-{[(BENZYLOXY)CARBONYL]AMINO}-4-{[(4-METHYLPHENYL)DIPHENYLMETHYL]CARBAMOYL}BUTANOICACID
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