Z-D-Leu-OSu

Z-D-Leu-OSu contains the amino acid side chain of D-leucine linked to a benzyloxycarbonyl (Z, Cbz) protected amino group and an N-hydroxysuccinimide ester (OSu) at the carboxylate, forming a peptide-coupling-ready derivative rather than a free amino acid. The molecule bears a secondary amide-forming functionality via the OSu ester, while the Z protecting group masks the α-amino group to control chemoselectivity during acylation chemistry, and the D stereochemistry is specified by the name. Z-D-Leu-OSu is used in synthesis and chemical biology workflows where activated amino acid esters support stepwise peptide bond formation or enable conjugation strategies that require an amino acid-derived acylating handle under controlled conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25973

CAS No:65581-25-1

Synonyms/Alias:Z-D-Leu-Osu;65581-25-1;(R)-2,5-Dioxopyrrolidin-1-yl2-(((benzyloxy)carbonyl)amino)-4-methylpentanoate;AmbotzZAA1206;CTK8G1603;MolPort-008-269-449;ZINC2526270;0056AC;AK-81061;KB-209782;N-alpha-Benzyloxycarbonyl-D-Leusuccinimidylester

Chemical Name:N-alpha-Benzyloxycarbonyl-D-leucine succinimidyl ester

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C18H22N2O6
M.W/Mr.
362,38 g/mole
Size
1 g;5 g;
InChI
1S/C18H22N2O6/c1-12(2)10-14(17(23)26-20-15(21)8-9-16(20)22)19-18(24)25-11-13-6-4-3-5-7-13/h3-7,12,14H,8-11H2,1-2H3,(H,19,24)/t14-/m1/s1
InChI Key
YHZUOMRURVTBMO-CQSZACIVSA-N
Canonical SMILES
CC(C)CC(C(=O)ON1C(=O)CCC1=O)NC(=O)OCC2=CC=CC=C2

Useful Tools

Peptide Calculator

Abbreviation List

Peptide Glossary

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

Featured Services
Peptide Synthesis ServicesEpitope Mapping ServicesCustom Conjugation ServicePeptide Modification ServicesPeptide Analysis ServicesPeptide CDMOcGMP Peptide ServicePeptide Nucleic Acids Synthesis
Hot Products
About us

Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

Our Customers

Creative Peptides customer logo 1 Creative Peptides customer logo 2 Creative Peptides customer logo 3 Creative Peptides customer logo 4 Creative Peptides customer logo 5 Creative Peptides customer logo 6 Creative Peptides customer logo 7 Creative Peptides customer logo 8 Creative Peptides customer logo 9 Creative Peptides customer logo 10 Creative Peptides customer logo 11 Creative Peptides customer logo 12 Creative Peptides customer logo 13 Creative Peptides customer logo 14 Creative Peptides customer logo 15 Creative Peptides customer logo 16 Creative Peptides customer logo 17 Creative Peptides customer logo 18 Creative Peptides customer logo 19 Creative Peptides customer logo 20 Creative Peptides customer logo 21 Creative Peptides customer logo 22 Creative Peptides customer logo 23 Creative Peptides customer logo 24 Creative Peptides client partner 1 Creative Peptides client partner 2 Creative Peptides client partner 3 Creative Peptides client partner 4 Creative Peptides client partner 5 Creative Peptides client partner 6 Creative Peptides client partner 7 Creative Peptides client partner 8 Creative Peptides client partner 9 Creative Peptides client partner 10 Creative Peptides client partner 11 Creative Peptides client partner 12 Creative Peptides client partner 13 Creative Peptides client partner 14 Creative Peptides client partner 15 Creative Peptides client partner 16 Creative Peptides client partner 17 Creative Peptides client partner 18 Creative Peptides client partner 19 Creative Peptides client partner 20 Creative Peptides client partner 21 Creative Peptides client partner 22 Creative Peptides client partner 23 Creative Peptides client partner 24