Z-D-Leucin is a protected amino acid derivative in which the amino group of D-leucine is carbobenzyloxy (benzyloxycarbonyl, Z/Cbz) protected, yielding a benzyl carbamate while retaining the leucine side chain. The molecule contains a free carboxylic acid functional group and a hydrophobic isobutyl side chain characteristic of leucine, with stereochemistry specified as the D configuration at the alpha carbon. Z-D-Leucin is used as a protected building block for controlled incorporation of D-leucine into peptides and peptide-related intermediates, including stepwise peptide synthesis workflows where the Z group helps manage chemoselectivity during coupling and deprotection steps.
CAT No: CP01315
CAS No:28862-79-5
Synonyms/Alias:N-Cbz-D-leucine;Z-D-Leu-OH;28862-79-5;Cbz-D-Leu-OH;Z-D-leucine;N-Benzyloxycarbonyl-D-leucine;(R)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoicacid;CBZ-D-LEUCINE;MFCD00066068;SBB028586;(2R)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoicacid;(2R)-4-methyl-2-[(phenylmethoxy)carbonylamino]pentanoicacid;Z-D-Leucin;PubChem10534;CBZ-D-LEUCIN;AC1OCSW7;N-Carbobenzoxy-D-leucine;96705_ALDRICH;SCHEMBL2366985;96705_FLUKA;CTK4G2300;MolPort-003-939-962;USPFMEKVPDBMCG-GFCCVEGCSA-N;Nalpha-benzyloxycarbonyl-D-leucine;ACT07750
2. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More