Z-D-Leucin

Z-D-Leucin is a protected amino acid derivative in which the amino group of D-leucine is carbobenzyloxy (benzyloxycarbonyl, Z/Cbz) protected, yielding a benzyl carbamate while retaining the leucine side chain. The molecule contains a free carboxylic acid functional group and a hydrophobic isobutyl side chain characteristic of leucine, with stereochemistry specified as the D configuration at the alpha carbon. Z-D-Leucin is used as a protected building block for controlled incorporation of D-leucine into peptides and peptide-related intermediates, including stepwise peptide synthesis workflows where the Z group helps manage chemoselectivity during coupling and deprotection steps.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01315

CAS No:28862-79-5

Synonyms/Alias:N-Cbz-D-leucine;Z-D-Leu-OH;28862-79-5;Cbz-D-Leu-OH;Z-D-leucine;N-Benzyloxycarbonyl-D-leucine;(R)-2-(((Benzyloxy)carbonyl)amino)-4-methylpentanoicacid;CBZ-D-LEUCINE;MFCD00066068;SBB028586;(2R)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoicacid;(2R)-4-methyl-2-[(phenylmethoxy)carbonylamino]pentanoicacid;Z-D-Leucin;PubChem10534;CBZ-D-LEUCIN;AC1OCSW7;N-Carbobenzoxy-D-leucine;96705_ALDRICH;SCHEMBL2366985;96705_FLUKA;CTK4G2300;MolPort-003-939-962;USPFMEKVPDBMCG-GFCCVEGCSA-N;Nalpha-benzyloxycarbonyl-D-leucine;ACT07750

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M.F/Formula
C14H19NO4
M.W/Mr.
265.3
Abbr
Z-D-Leu-OH
InChI
1S/C14H19NO4/c1-10(2)8-12(13(16)17)15-14(18)19-9-11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3,(H,15,18)(H,16,17)/t12-/m1/s1
InChI Key
USPFMEKVPDBMCG-GFCCVEGCSA-N
Canonical SMILES
CC(C)CC(C(=O)O)NC(=O)OCC1=CC=CC=C1

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