Z-D-1-Nal-OH is a protected, D-configured amino acid derivative in which the amino acid framework is based on 1-naphthylalanine (Nal) and bears a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality. The molecule contains a free carboxylic acid (-COOH) and a Z-carbamate-protected amine (-NH-COO-CH2-Ph), with the aromatic 1-naphthyl side chain providing a hydrophobic, π-rich group for noncovalent interactions in peptide-like structures. In synthesis and chemical biology workflows, this protected amino acid is used as a substrate building block for stepwise peptide assembly or for preparing labeled and structurally defined Nal-containing peptides and analogues, where the Z group helps control chemoselectivity during coupling steps.
CAT No: CP27611
CAS No:96402-43-6
Synonyms/Alias:Cbz-3-(1-naphthyl)-D-Ala;96402-43-6;AC1ODU1J;Z-D-1-NAL-OH;SCHEMBL10976664;HNYQEAGTPQSPLT-LJQANCHMSA-N;ZINC2567687;6522AH;N-benzyloxycarbonyl-3-(1-naphthyl)-D-alanine;(2R)-3-naphthalen-1-yl-2-(phenylmethoxycarbonylamino)propanoicacid;(2R)-2-{[(benzyloxy)carbonyl]amino}-3-naphthalen-1-ylpropanoicacid;1-Naphthalenepropanoicacid,a-[[(phenylmethoxy)carbonyl]amino]-,(aR)-
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