Z-D-Pro-OSu

Name: Z-D-Pro-OSu
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-D-Pro-OSu is a protected amino acid derivative consisting of D-proline bearing a benzyloxycarbonyl (Z, Cbz) protecting group on the amino function and a proline side chain that forms a cyclic secondary amine-containing ring. The molecule presents a carboxyl group converted to an N-hydroxysuccinimide ester (OSu), creating an activated acylating functionality while retaining the ester-linked succinimide leaving group and the ring nitrogen as part of the proline scaffold. Z-D-Pro-OSu is used as an acylating intermediate for peptide coupling and amide-bond formation in solution or on solid supports, and the OSu activation supports labeling or conjugation workflows that require controlled transfer of the proline carbonyl.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25129

CAS No:104055-24-5

Synonyms/Alias:Z-D-PRO-OSU;104055-24-5;N-alpha-Benzyloxycarbonyl-D-Prosuccinimidylester;AmbotzZAA1211;AC1LEHRF;SCHEMBL10347014;CTK8E9770;MolPort-008-269-453;ZINC156805;ZINC00156805;RT-014255;1-O-benzyl2-O-(2,5-dioxopyrrolidin-1-yl)(2R)-pyrrolidine-1,2-dicarboxylate

Chemical Name:N-alpha-Benzyloxycarbonyl-D-proline succinimidyl ester

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cGMP Peptide

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Drug master files (DMF) filing

M.F/Formula

C17H18N2O6

M.W/Mr.

346,33 g/mole

Size

1 g;5 g;

InChI

1S/C17H18N2O6/c20-14-8-9-15(21)19(14)25-16(22)13-7-4-10-18(13)17(23)24-11-12-5-2-1-3-6-12/h1-3,5-6,13H,4,7-11H2/t13-/m1/s1

InChI Key

BDNYCEKWUBRCBJ-CYBMUJFWSA-N

Canonical SMILES

C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O

1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy

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3. The effect of B-type allatostatin neuropeptides on crosstalk between the insect immune response and cold tolerance

4. The spatiotemporal control of signalling and trafficking of the GLP-1R

5. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line

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