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  5. Z-D-Thr(Bzl)-OH · DCHA

Z-D-Thr(Bzl)-OH · DCHA

Z-D-Thr(Bzl)-OH · DCHA is a protected amino acid derivative of threonine in which the amino group is carbobenzyloxy (Z/Cbz) protected and the side-chain hydroxyl is benzyl (Bzl) protected, with the carboxylic acid present as a free acid and the stereochemical designation given as D. The molecule contains a benzylic ester-forming carbamate protecting group on nitrogen, a benzyl ether on the threonine side-chain oxygen, and forms a DCHA salt association that modulates the handling and physicochemical properties of the compound relative to the free base. It is used as a building block for peptide synthesis and for preparing threonine-containing peptide analogues where orthogonal protection of the side-chain hydroxyl supports controlled deprotection and subsequent coupling steps.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26703

CAS No:201276-12-2

Synonyms/Alias:AKOS024259142;AK-89016;Dicyclohexylamine(2R,3S)-3-(benzyloxy)-2-(((benzyloxy)carbonyl)amino)butanoate;201276-12-2

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cGMP Peptide
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M.F/Formula
C31H44N2O5
M.W/Mr.
524.7
Size
1 g;5 g;
InChI
1S/C19H21NO5.C12H23N/c1-14(24-12-15-8-4-2-5-9-15)17(18(21)22)20-19(23)25-13-16-10-6-3-7-11-16;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h2-11,14,17H,12-13H2,1H3,(H,20,23)(H,21,22);11-13H,1-10H2/t14-,17+;/m0./s1
InChI Key
FBQGKIIVCFVSBB-SQQLFYIASA-N
Canonical SMILES
CC(C(C(=O)O)NC(=O)OCC1=CC=CC=C1)OCC2=CC=CC=C2.C1CCC(CC1)NC2CCCCC2

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