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Z-D-Tic-OH

Z-D-Tic-OH is a protected, non-proteinogenic amino acid derivative featuring the side chain of Tic (tetrahydroisoquinoline-3-carboxylic acid) in a D stereochemical form, with the amino group protected as a benzyloxycarbonyl (Z, Cbz) carbamate. The molecule contains both a free carboxylic acid (-COOH) and a carbamate-protected amino functionality, with the Z group serving to suppress undesired amine reactivity during stepwise peptide coupling chemistry. Z-D-Tic-OH is used as a building block for preparing peptides and peptide analogues that incorporate the Tic residue for structure-activity studies, chemical biology conjugation strategies, and synthetic access to conformationally constrained amino acid motifs.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26401

CAS No:146684-74-4

Synonyms/Alias:Z-D-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid;146684-74-4;Z-D-TIC-OH;(R)-(-)-2-(Benzyloxycarbonyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylicacid;Z-[3R]-1,2,3,4-Tetrahydroisoquinolene-3-carboxylicacid;(3R)-2-[(benzyloxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid;AC1LELSX;SCHEMBL14862925;CTK8F0569;ZINC57070;MolPort-003-990-208;AJ-09565;DB-042856;RT-016323;V3380;(3R)-2-Carbobenzoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid;(3R)-2-phenylmethoxycarbonyl-3,4-dihydro-1H-isoquinoline-3-carboxylicacid

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M.F/Formula
C18H17NO4
M.W/Mr.
311.34
Size
1 g;5 g;
InChI
1S/C18H17NO4/c20-17(21)16-10-14-8-4-5-9-15(14)11-19(16)18(22)23-12-13-6-2-1-3-7-13/h1-9,16H,10-12H2,(H,20,21)/t16-/m1/s1
InChI Key
YWVQGUBCAUFBCP-MRXNPFEDSA-N
Canonical SMILES
C1C(N(CC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3)C(=O)O

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