Z-gamma-carboxy-DL-Glu(OtBu)2-OH is a protected, nonstandard glutamate derivative featuring a gamma-carboxylated side chain (gamma-glutamate motif) and a DL stereochemical mixture at the amino acid center, with the amino group masked as a Z (benzyloxycarbonyl, Cbz-like) carbamate. The molecule bears two tert-butyl ester protecting groups on the side-chain carboxyl functionality, while the free carboxylic acid at the alpha position remains available for further coupling chemistry, yielding a protected amino acid intermediate with both carbamate and ester protection that controls chemoselectivity during synthesis. In peptide and amino-acid-derivative synthesis, it is employed as a stepwise building block to introduce gamma-carboxylated glutamate units into longer peptide frameworks and to support structure-activity studies or analytical labeling strategies that require a protected, multifunctional glutamate analogue.
CAT No: CP27223
CAS No:56877-43-1
Synonyms/Alias:L-lysine;lysine;56-87-1;lysineacid;h-Lys-oh;(S)-Lysine;Aminutrin;L-(+)-Lysine;alpha-Lysine;L-lys;(2S)-2,6-diaminohexanoicacid;(S)-2,6-Diaminohexanoicacid;Lysine,L-;Lysinum[Latin];(S)-alpha,epsilon-Diaminocaproicacid;Lisina[Spanish];L-Norleucine,6-amino-;lysin;(S)-2,6-Diaminocaproicacid;Lysinum;a-Lysine;L-Lysin;LYS(IUPACabbreviation);L-2,6-Diaminocaproicacid;6-amino-Aminutrin
4. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die
5. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
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