Z-glycine N-hydroxysuccinimide ester

Name: Z-glycine N-hydroxysuccinimide ester
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-glycine N-hydroxysuccinimide ester contains a glycine backbone bearing a benzyloxycarbonyl (Z) protecting group on the amino functionality and an N-hydroxysuccinimide (NHS) ester on the carboxyl group, classifying it as a protected amino acid derivative. The molecule therefore presents a carbamate-protected amine and an activated carboxylate equivalent (the NHS ester), with the Z group serving to suppress undesired amine reactivity during conjugation or peptide-related steps. In synthesis and chemical biology workflows, this activated ester form is employed as a precursor for forming amide linkages with nucleophiles such as primary amines, enabling stepwise construction of glycine-containing conjugates and labeling reagents under conditions that preserve the protected amino group.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00913

CAS No:2899-60-7

Synonyms/Alias:2899-60-7;Z-Gly-OSu;2,5-Dioxopyrrolidin-1-yl2-(((benzyloxy)carbonyl)amino)acetate;Z-glycineN-succinimidylester;2,5-dioxopyrrolidin-1-yln-[(benzyloxy)carbonyl]glycinate;Glycine,N-[(phenylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinylester;Maybridge4_002581;2,5-dioxopyrrolidin-1-yl2-{[(benzyloxy)carbonyl]amino}acetate;AC1L2QCA;AC1Q6LLE;96185_ALDRICH;SCHEMBL1412214;96185_FLUKA;CTK8B4389;MolPort-000-884-403;WSCWXNZWFZXKEH-UHFFFAOYSA-N;HMS1528F07;ZINC171261;EINECS220-789-7;Z-glycineN-hydroxysuccinimideester;ANW-44893;AR-1D4519;STK097588;ZINC00171261;AKOS000281778

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cGMP Peptide

Registration of APIs
CMC information required for an IND

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Drug master files (DMF) filing

M.F/Formula

C14H14N2O6

M.W/Mr.

306.3

Abbr

Z-Gly-OSu

InChI

1S/C14H14N2O6/c17-11-6-7-12(18)16(11)22-13(19)8-15-14(20)21-9-10-4-2-1-3-5-10/h1-5H,6-9H2,(H,15,20)

InChI Key

WSCWXNZWFZXKEH-UHFFFAOYSA-N

Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)CNC(=O)OCC2=CC=CC=C2

1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

2. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

3. Implications of ligand-receptor binding kinetics on GLP-1R signalling

4. Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

5. C-peptide and its C-terminal fragments improve erythrocyte deformability in type 1 diabetes patients

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