Z-glycine N-hydroxysuccinimide ester

Z-glycine N-hydroxysuccinimide ester contains a glycine backbone bearing a benzyloxycarbonyl (Z) protecting group on the amino functionality and an N-hydroxysuccinimide (NHS) ester on the carboxyl group, classifying it as a protected amino acid derivative. The molecule therefore presents a carbamate-protected amine and an activated carboxylate equivalent (the NHS ester), with the Z group serving to suppress undesired amine reactivity during conjugation or peptide-related steps. In synthesis and chemical biology workflows, this activated ester form is employed as a precursor for forming amide linkages with nucleophiles such as primary amines, enabling stepwise construction of glycine-containing conjugates and labeling reagents under conditions that preserve the protected amino group.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00913

CAS No:2899-60-7

Synonyms/Alias:2899-60-7;Z-Gly-OSu;2,5-Dioxopyrrolidin-1-yl2-(((benzyloxy)carbonyl)amino)acetate;Z-glycineN-succinimidylester;2,5-dioxopyrrolidin-1-yln-[(benzyloxy)carbonyl]glycinate;Glycine,N-[(phenylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinylester;Maybridge4_002581;2,5-dioxopyrrolidin-1-yl2-{[(benzyloxy)carbonyl]amino}acetate;AC1L2QCA;AC1Q6LLE;96185_ALDRICH;SCHEMBL1412214;96185_FLUKA;CTK8B4389;MolPort-000-884-403;WSCWXNZWFZXKEH-UHFFFAOYSA-N;HMS1528F07;ZINC171261;EINECS220-789-7;Z-glycineN-hydroxysuccinimideester;ANW-44893;AR-1D4519;STK097588;ZINC00171261;AKOS000281778

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M.F/Formula
C14H14N2O6
M.W/Mr.
306.3
Abbr
Z-Gly-OSu
InChI
1S/C14H14N2O6/c17-11-6-7-12(18)16(11)22-13(19)8-15-14(20)21-9-10-4-2-1-3-5-10/h1-5H,6-9H2,(H,15,20)
InChI Key
WSCWXNZWFZXKEH-UHFFFAOYSA-N
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)CNC(=O)OCC2=CC=CC=C2

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