Z-L-2-aminobutyric acid

Name: Z-L-2-aminobutyric acid
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-L-2-aminobutyric acid is a protected amino acid derivative classified as an amino acid with a 2-aminobutyric acid backbone, bearing the Z (benzyloxycarbonyl, Cbz) protecting group on the amino functionality and the free carboxylic acid group characteristic of amino acid intermediates. The molecule contains a stereogenic center consistent with the "L" designation in its name, and its side chain is a short aliphatic substituent that provides a hydrophobic, non-aromatic functionality while the protected nitrogen prevents unselective amide formation during synthesis. Z-L-2-aminobutyric acid is used in peptide chemistry as a protected building block for stepwise assembly and for controlling chemoselectivity when preparing amino acid derivatives and related peptide intermediates.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP02906

CAS No:42918-86-5

Synonyms/Alias:(S)-2-(((Benzyloxy)carbonyl)amino)butanoicacid;42918-86-5;(2S)-2-{[(benzyloxy)carbonyl]amino}butanoicacid;(S)-2-(Bezyloxycarbonylamino)butanoicacid;Z-2-Abu-OH;(S)-2-(BENZYLOXYCARBONYLAMINO)BUTANOICACID;Cbz-Abu-OH;AmbotzZAA1200;PubChem18943;AC1OL9QL;SCHEMBL265512;MolPort-001-794-480;SZQMTCSQWUYUML-JTQLQIEISA-N;ZINC4762225;MFCD00077006;AKOS016842415;CS12071;AJ-52189;AK-35139;BR-35139;AB0024888;ST24026523;W6246;S-1588;(2S)-2-(phenylmethoxycarbonylamino)butanoicacid

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cGMP Peptide

Registration of APIs
CMC information required for an IND

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M.F/Formula

C12H15NO4

M.W/Mr.

237.3

Abbr

Z-2-Abu-OH

InChI

1S/C12H15NO4/c1-2-10(11(14)15)13-12(16)17-8-9-6-4-3-5-7-9/h3-7,10H,2,8H2,1H3,(H,13,16)(H,14,15)/t10-/m0/s1

InChI Key

SZQMTCSQWUYUML-JTQLQIEISA-N

Canonical SMILES

CCC(C(=O)O)NC(=O)OCC1=CC=CC=C1

1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

2. Oleic acid and glucose regulate glucagon-like peptide 1 receptor expression in a rat pancreatic ductal cell line

3. Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L

4. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

5. Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis

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