Z-L-aspartic acid di-tert.butyl ester is a protected L-aspartic acid derivative in which the side-chain carboxyl group and the amino acid carboxyl functionality are converted to tert-butyl ester groups, while the amino group is protected as a Z (benzyloxycarbonyl, Cbz-type) carbamate. The molecule therefore contains two ester carbonyls and a carbamate-linked nitrogen, with the aspartate side chain retaining the β-carboxyl substitution pattern characteristic of aspartic acid but masked as tert-butyl esters to reduce free-carboxyl reactivity. In peptide synthesis and related derivative preparation, it functions as a stepwise-protected amino acid building block that can be used to control chemoselectivity by preventing undesired carboxyl participation until deprotection and subsequent coupling steps.
CAT No: CP00440
CAS No:42417-76-5
Synonyms/Alias:42417-76-5;Z-ASP(OTBU)-OTBU;C20H29NO6;ZINC2562529;Z-L-asparticaciddi-tert.butylester;AM81627;Z-L-asparticaciddi-tert??butylester;X5781;K-8812;N-(Benzyloxycarbonyl)-3-(tert-butyloxycarbonyl)-L-alaninetert-butylester;L-Asparticacid,N-[(phenylmethoxy)carbonyl]-,1,4-bis(1,1-dimethylethyl)ester
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