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Z-L-Gln-OSu

Z-L-Gln-OSu is a protected amino acid derivative in which L-glutamine is converted to a glutaminyl N-carboxyanhydride-type activated ester (OSu) while the α-amino group is protected by a benzyloxycarbonyl (Z, Cbz) group. The molecule contains a free carboxylate equivalent as the N-succinimidyl ester (OSu) and a side-chain amide functionality characteristic of glutamine, with the stereochemistry indicated as L in the product name. Z-L-Gln-OSu is used as an activated amino acid building block for peptide coupling and for preparing glutaminyl-containing peptide intermediates or conjugates in solution-phase or solid-phase synthesis workflows where an electrophilic ester enables amide bond formation with nucleophiles.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25779

CAS No:34078-85-8

Synonyms/Alias:Z-Gln-OSu;34078-85-8;AmbotzZAA1219;Z-L-Gln-OSu;SCHEMBL16385082;CTK8G3859;MolPort-008-269-456;C17H19N3O7;4054AB;ZINC71788219;AKOS016003264;AK-81324;KB-281504;ST24031989;2,5-Dioxo-1-pyrrolidinylN~2~-[(benzyloxy)carbonyl]-L-glutaminate;[(S)-4-Amino-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-4-oxobutyl]carbamicacidbenzylester

Chemical Name:N-alpha-Benzyloxycarbonyl-L-glutamine succinimidyl ester

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M.F/Formula
C17H19N3O7
M.W/Mr.
377,35 g/mole
Size
25 g;100 g;
InChI
1S/C17H19N3O7/c18-13(21)7-6-12(16(24)27-20-14(22)8-9-15(20)23)19-17(25)26-10-11-4-2-1-3-5-11/h1-5,12H,6-10H2,(H2,18,21)(H,19,25)/t12-/m0/s1
InChI Key
KAADPWIOJORBEB-LBPRGKRZSA-N
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)C(CCC(=O)N)NC(=O)OCC2=CC=CC=C2

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