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Z-L-Glu-OMe

Z-L-Glu-OMe contains L-glutamic acid in a methyl ester form (Glu-OMe) with a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality, yielding a protected amino acid ester suitable for peptide-related synthesis. The molecule features a free carboxylate ester (-COOCH3) and a side-chain γ-carboxylate that remains as the glutamate functionality, while the Z carbamate masks the α-amino group to reduce undesired amide/urea formation during coupling. Z-L-Glu-OMe is used as a stepwise building block or intermediate in peptide synthesis and related derivatization workflows where controlled chemoselectivity of the α-amino group and preservation of glutamate side-chain reactivity are required for assembling more complex amino acid and peptide derivatives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25904

CAS No:5672-83-3

Synonyms/Alias:AC-ILE-NH2;Acetyl-L-isoleucineamide;56711-06-9;AC1OCUTB;SCHEMBL10137041;CTK8F7538;ZINC399500;6094AH;KM0025;AKOS006275706;ZB012789;(2S,3S)-2-acetamido-3-methylpentanamide

Chemical Name:N-alpha-Benzyloxycarbonyl-L-glutamic acid alpha-methyl ester

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cGMP Peptide
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  • Drug master files (DMF) filing
M.F/Formula
C8H16N2O2
M.W/Mr.
295,29 g/mole
Size
1 g;5 g;25 g;
InChI
1S/C8H16N2O2/c1-4-5(2)7(8(9)12)10-6(3)11/h5,7H,4H2,1-3H3,(H2,9,12)(H,10,11)/t5-,7-/m0/s1
InChI Key
WFBXRBMLCXMBBM-FSPLSTOPSA-N
Canonical SMILES
CCC(C)C(C(=O)N)NC(=O)C

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