Z-L-Glu-OMe

Name: Z-L-Glu-OMe
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-L-Glu-OMe contains L-glutamic acid in a methyl ester form (Glu-OMe) with a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality, yielding a protected amino acid ester suitable for peptide-related synthesis. The molecule features a free carboxylate ester (-COOCH3) and a side-chain γ-carboxylate that remains as the glutamate functionality, while the Z carbamate masks the α-amino group to reduce undesired amide/urea formation during coupling. Z-L-Glu-OMe is used as a stepwise building block or intermediate in peptide synthesis and related derivatization workflows where controlled chemoselectivity of the α-amino group and preservation of glutamate side-chain reactivity are required for assembling more complex amino acid and peptide derivatives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25904

CAS No:5672-83-3

Synonyms/Alias:AC-ILE-NH2;Acetyl-L-isoleucineamide;56711-06-9;AC1OCUTB;SCHEMBL10137041;CTK8F7538;ZINC399500;6094AH;KM0025;AKOS006275706;ZB012789;(2S,3S)-2-acetamido-3-methylpentanamide

Chemical Name:N-alpha-Benzyloxycarbonyl-L-glutamic acid alpha-methyl ester

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C8H16N2O2

M.W/Mr.

295,29 g/mole

Size

1 g;5 g;25 g;

InChI

1S/C8H16N2O2/c1-4-5(2)7(8(9)12)10-6(3)11/h5,7H,4H2,1-3H3,(H2,9,12)(H,10,11)/t5-,7-/m0/s1

InChI Key

WFBXRBMLCXMBBM-FSPLSTOPSA-N

Canonical SMILES

CCC(C)C(C(=O)N)NC(=O)C

1. Implications of ligand-receptor binding kinetics on GLP-1R signalling

2. Genetic, cellular, and structural characterization of the membrane potential-dependent cell-penetrating peptide translocation pore

3. TMEM16F and dynamins control expansive plasma membrane reservoirs

4. Quantitative Analysis of Ligands Effects on Bioefficacy of Nanoemulsion encapsulating Depigmenting Active

5. Odorant binding protein based biomimetic sensors for detection of alcohols associated with Salmonella contamination in packaged beef

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