Z-L-Leucine N-carboxyanhydride is a cyclic N-carboxyanhydride (NCA) derived from the amino acid L-leucine, bearing a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality. The NCA ring activates the carboxyl-derived carbonyl toward nucleophilic ring opening while retaining the leucine side chain, which is characterized by a hydrophobic isobutyl group, and the molecule contains the reactive N-carboxyanhydride carbonyl system alongside the protected carbamate. It is used as a monomer for controlled peptide or polypeptide synthesis via NCA polymerization or stepwise chain growth, providing a protected leucine residue for incorporation into peptide backbones under conditions that promote NCA ring-opening.
CAT No: CP01321
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