Z-L-Lys(Z)-ONp is a protected lysine amino acid derivative featuring a side-chain ε-amino group and an α-amino acid backbone in which both the α-amino functionality and the ε-amino functionality are protected as benzyloxycarbonyl (Z) carbamates, while the carboxyl group is converted to an ONp ester (p-nitrophenyl ester). The molecule therefore contains two Z-protected amide-forming nitrogen atoms and a p-nitrophenyl oxy leaving group at the carboxylate, with the "Z-L-Lys" naming indicating L-configuration at the α-carbon. In peptide chemistry, the carboxyl ONp ester and the orthogonally protected lysine nitrogens provide a protected, activated building block for controlled coupling and for preparing lysine-containing peptide intermediates or labeled/modified peptide fragments under conditions that require chemoselective handling of the protected amino groups.
CAT No: CP25606
CAS No:2116-82-7
Chemical Name:N-alpha-N-epsilon-Bis-benzyloxycarbonyl-L-lysine p-nitrophenyl ester
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