Z-L-Phe-OSu

Name: Z-L-Phe-OSu
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-L-Phe-OSu is a protected amino acid derivative consisting of L-phenylalanine bearing an N-benzyloxycarbonyl (Z, Cbz) protecting group and a reactive N-hydroxysuccinimide (OSu) ester at the carboxyl terminus. The molecule contains a carbamate-protected amino functionality and an activated ester that can undergo nucleophilic acyl substitution, while the phenyl side chain provides a hydrophobic aromatic group for residue-level structure-property studies. Z-L-Phe-OSu is used in peptide coupling and bioconjugation workflows as an activated amino acid building block that can form amide bonds with nucleophiles such as amines under standard acylation conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25775

CAS No:3397-32-8

Synonyms/Alias:Z-PHE-OSU;3397-32-8;C21H20N2O6;AmbotzZAA1237;SCHEMBL5689118;MolPort-006-115-310;7956AH;ZINC71788225;AKOS016369135;MCULE-6019819182;AK170092;KB-105428;FT-0698281;K-7793;N-(Benzyloxycarbonyl)-L-phenylalaninesuccinimidylester;N-Benzyloxycarbonylphenylalanine-N-hydroxysuccinimideester;L-Phenylalanine,N-[(phenylmethoxy)carbonyl]-,2,5-dioxo-1-pyrrolidinylester

Chemical Name:N-alpha-Benzyloxycarbonyl-L-phenylalanine succinimidyl ester

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cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C21H20N2O6

M.W/Mr.

396,38 g/mole

Size

5 g;25 g;

InChI

1S/C21H20N2O6/c24-18-11-12-19(25)23(18)29-20(26)17(13-15-7-3-1-4-8-15)22-21(27)28-14-16-9-5-2-6-10-16/h1-10,17H,11-14H2,(H,22,27)/t17-/m0/s1

InChI Key

MOJNKVWQJKPXCT-KRWDZBQOSA-N

Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

1. The spatiotemporal control of signalling and trafficking of the GLP-1R

2. Investigating Potential Interactions Between Neurohypophyseal Peptides, their Drug Analogs, and Coagulation Factor VIII

3. Myotropic activity of allatostatins in tenebrionid beetles

4. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

5. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment

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