Z-L-Phenylalanine N-carboxyanhydride is a phenylalanine-derived N-carboxyanhydride (NCA) in which the amino acid nitrogen is incorporated into a cyclic anhydride, bearing a Z (benzyloxycarbonyl) protecting group on the nitrogen and a phenyl side chain characteristic of L-phenylalanine. The molecule contains the reactive NCA carbonyl functionality within the anhydride ring alongside the benzyloxycarbonyl (Z) carbamate and the pendant benzyl-substituted phenyl group, with stereochemistry corresponding to the L-phenylalanine precursor as indicated by the product name. It is employed as a peptide-building intermediate in controlled polymerization and solid-phase or solution-phase peptide synthesis workflows, where the NCA ring can undergo ring-opening to generate growing peptide chains with phenylalanine residues under conditions compatible with carbamate-protected termini.
CAT No: CP01626
CAS No:25613-60-9
Synonyms/Alias:25613-60-9;Z-PHE-NCA;Z-L-PhenylalanineN-carboxyanhydride;ZINC100118931;HE024503;3-(Benzyloxycarbonyl)-4beta-benzyloxazolidine-2,5-dione;3-Oxazolidinecarboxylicacid,2,5-dioxo-4-(phenylmethyl)-,phenylmethylester,(4S)-
2. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
5. High fat diet and GLP-1 drugs induce pancreatic injury in mice
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