1. Home
  2. Products
  3. Amino Acids
  4. Amino Acids & Derivatives
  5. Z-L-Pip-OH

Z-L-Pip-OH

Z-L-Pip-OH is a protected amino acid derivative featuring L-pipecolic acid (L-Pip) in which the amino functionality is masked by a benzyloxycarbonyl (Z, Cbz) protecting group, while the molecule retains a free carboxylic acid (-COOH) for subsequent coupling chemistry. The structure therefore presents a Cα stereocenter consistent with the L designation and a saturated six-membered ring side chain (pipecolate) bearing a secondary amine-free cyclic framework, with the Z carbamate controlling chemoselectivity by preventing unprotected amine reactivity during peptide or amide bond formation. Z-L-Pip-OH is used as a building block for stepwise peptide synthesis and for preparing more complex amino acid and peptide derivatives where controlled protection of the amino group supports sequential functionalization and purification by standard organic chemistry workflows.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25707

CAS No:28697-09-8

Synonyms/Alias:28697-09-8;(R)-1-((Benzyloxy)carbonyl)piperidine-2-carboxylicacid;(R)-(+)-1-Cbz-2-piperidinecarboxylicacid;N-Cbz-(R)-(+)-pipecolinicacid;(D)-N-(BENZYLOXYCARBONYL)PIPECOLICACID;(D)-N-CBZ-PIPECOLICACID;(R)-1-(Benzyloxycarbonyl)-2-piperidinecarboxylicAcid;(R)-1-CBZ-PIPERIDINE-2-CARBOXYLICACID;(2R)-1-[(BENZYLOXY)CARBONYL]PIPERIDINE-2-CARBOXYLICACID;AmbotzZAA1005;PubChem6270;AC1LELW3;Z-L-PIP-OH;AC1Q71DO;AC1Q71DP;SCHEMBL82714;1,2-Piperidinedicarboxylicacid,1-(phenylmethyl)ester,(2R)-;516376_ALDRICH;N-Carbobenzoxy-D-pipecolicAcid;N-CBZ-D-PIPECOLINICACID;CTK4G1935;ZINC57123;MolPort-001-794-620;ZSAIHAKADPJIGN-GFCCVEGCSA-N;AKOS010366802

Chemical Name:(R)-(+)-N-Benzyloxycarbonyl-pipecolinic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C14H17NO4
M.W/Mr.
263,3 g/mole
Size
1 g;5 g;25 g;
InChI
1S/C14H17NO4/c16-13(17)12-8-4-5-9-15(12)14(18)19-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2,(H,16,17)/t12-/m1/s1
InChI Key
ZSAIHAKADPJIGN-GFCCVEGCSA-N
Canonical SMILES
C1CCN(C(C1)C(=O)O)C(=O)OCC2=CC=CC=C2

Useful Tools

Peptide Calculator

Abbreviation List

Peptide Glossary

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

Featured Services
Peptide Analysis ServicesEpitope Mapping ServicesPeptide Modification ServicesPeptide Nucleic Acids SynthesisCustom Conjugation ServicePeptide Synthesis ServicesPeptide CDMOcGMP Peptide Service
Hot Products
DOTA-cyclo(RGDfK) acetate

DOTA-cyclo(RGDfK) acetate is a metal-chelating cyclic RGD peptide used to investigate integrin-binding motifs. Its cyclized structure stabilizes ligand presentation for receptor-targeting studies. Researchers analyze its conformation for high-affinity binding models. The DOTA moiety supports imaging-related biochemical experiments.

Read More Read More
Terlipressin Acetate

Terlipressin Acetate is a synthetic vasopressin analog peptide used for vascular and liver research. Buy Terlipressin peptide powder online from a trusted peptide supplier for professional studies.

Read More Read More
Fertirelin Acetate

Fertirelin Acetate is a synthetic peptide that promotes ovulation and fertility. Purchase Fertirelin research peptide for breeding and hormonal studies.

Read More Read More
Atosiban

Atosiban is a peptide oxytocin receptor antagonist that helps prevent preterm labor. Buy Atosiban peptide for reproductive and uterine contractility research.

Read More Read More
Lanreotide Acetate

Lanreotide Acetate is a somatostatin analog peptide regulating hormone secretion. Purchase Lanreotide peptide online to study tumor suppression and endocrine disorders.

Read More Read More
Deslorelin

Deslorelin peptide is a potent GnRH agonist used for fertility and hormonal control. Buy Deslorelin peptide powder online for veterinary and endocrine research applications.

Read More Read More
GLP-1 (7-36) amide Acetate

GLP-1 (7-36) amide Acetate peptide enhances insulin secretion and glucose balance. Buy this research peptide for diabetes and metabolic disorder studies.

Read More Read More
Gonadorelin Acetate

Gonadorelin Acetate stimulates LH and FSH release in fertility research. Purchase Gonadorelin peptide powder from a verified peptide supplier for reproductive studies.

Read More Read More
Thymosin β4 Acetate

Thymosin β4 Acetate promotes wound healing, tissue repair, and cell regeneration. Buy Thymosin beta 4 peptide powder for research on recovery and regenerative medicine.

Read More Read More
Angiotensin II

Angiotensin II peptide regulates blood pressure and vascular constriction. Purchase this synthetic research peptide to support cardiovascular and renal function studies.

Read More Read More
About us

Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

Our Customers